Second malignancies among survivors of germ-cell testicular cancer : A pooled analysis between 13 cancer registries
Identifieur interne : 009366 ( Main/Exploration ); précédent : 009365; suivant : 009367Second malignancies among survivors of germ-cell testicular cancer : A pooled analysis between 13 cancer registries
Auteurs : Lorenzo Richiardi [Italie] ; Ghislaine Scelo [France] ; Paolo Boffetta [France] ; Kari Hemminki [Allemagne, Suède] ; Eero Pukkala [Finlande] ; Jorgen H. Olsen [Danemark] ; Elisabete Weiderpass [Norvège, Suède] ; Elizabeth Tracey [Australie] ; David H. Brewster [Royaume-Uni] ; Mary L. Mcbride [Canada] ; Erich V. Kliewer [Canada, Australie] ; Jon M. Tonita [Canada] ; Vera Pompe-Kirn [Slovénie] ; Chia Kee-Seng [Singapour] ; Jou G. Jonasson [Islande] ; Carmen Martos [Espagne] ; Paul Brennan [France]Source :
- International journal of cancer [ 0020-7136 ] ; 2007.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
Abstract
We investigated the risk of second malignancies among 29,511 survivors of germ-cell testicular cancer recorded in 13 cancer registries. Standardized incidence ratios (SIRs) were estimated comparing the observed numbers of second malignancies with the expected numbers obtained from sex-, age-, period- and population-specific incidence rates. Seminomas and nonseminomas, the 2 main histological groups of testicular cancer, were analyzed separately. During a median follow-up period of 8.3 years (0-35 years), we observed 1,811 second tumors, with a corresponding SIR of 1.65 (95% confidence interval (CI): 1.57-1.73). Statistically significant increased risks were found for fifteen cancer types, including SIRs of 2.0 or higher for cancers of the stomach, gallbladder and bile ducts, pancreas, bladder, kidney, thyroid, and for soft-tissue sarcoma, nonmelanoma skin cancer and myeloid leukemia. The SIR for myeloid leukemia was 2.39 (95% CI: 1.41-3.77) after seminomas, and 6.77 (95% CI: 4.14-10.5) after nonseminomas. It increased to 37.9 (95% CI: 18.9-67.8; based on 11 observed cases of leukemia) among nonseminoma patients diagnosed since 1990. SIRs for most solid cancers increased with follow-up duration, whereas they did not change with year of testicular cancer diagnosis. Among subjects diagnosed before 1980, 20 year survivors of seminoma had a cumulative risk of solid cancer of 9.6% (95% CI: 8.7-10.5%) vs. 6.5% expected, whereas 20 years survivors of nonseminoma had a risk of 5.0% (95% CI: 4.2-6.0%) vs. 3.1% expected. In conclusion, survivors of testicular cancers have an increased risk of several second primaries, where the effect of the treatment seems to play a major role.
Affiliations:
- Allemagne, Australie, Canada, Danemark, Espagne, Finlande, France, Islande, Italie, Norvège, Royaume-Uni, Singapour, Slovénie, Suède
- Auvergne-Rhône-Alpes, Bade-Wurtemberg, District de Karlsruhe, Hovedstaden, Manitoba, Nouvelle-Galles du Sud, Rhône-Alpes, Svealand, Østlandet
- Copenhague, Heidelberg, Lyon, Oslo, Stockholm, Sydney, Winnipeg
- Université de Sydney, Université du Manitoba
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Tonita</name><affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Saskatchewan Cancer Agency</s1><s2>Regina, SK</s2><s3>CAN</s3><sZ>12 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Saskatchewan Cancer Agency</wicri:noRegion></affiliation></author><author><name sortKey="Pompe Kirn, Vera" sort="Pompe Kirn, Vera" uniqKey="Pompe Kirn V" first="Vera" last="Pompe-Kirn">Vera Pompe-Kirn</name><affiliation wicri:level="1"><inist:fA14 i1="16"><s1>Cancer Registry of Slovenia, Institute of Oncology</s1><s2>Ljubljana</s2><s3>SVN</s3><sZ>13 aut.</sZ></inist:fA14><country>Slovénie</country><wicri:noRegion>Ljubljana</wicri:noRegion></affiliation></author><author><name sortKey="Kee Seng, Chia" sort="Kee Seng, Chia" uniqKey="Kee Seng C" first="Chia" last="Kee-Seng">Chia Kee-Seng</name><affiliation wicri:level="1"><inist:fA14 i1="17"><s1>Center for Molecular Epidemiology</s1><s3>SGP</s3><sZ>14 aut.</sZ></inist:fA14><country>Singapour</country><wicri:noRegion>Center for Molecular Epidemiology</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="18"><s1>Singapore Cancer Registry</s1><s3>SGP</s3><sZ>14 aut.</sZ></inist:fA14><country>Singapour</country><wicri:noRegion>Singapore Cancer Registry</wicri:noRegion></affiliation></author><author><name sortKey="Jonasson, Jou G" sort="Jonasson, Jou G" uniqKey="Jonasson J" first="Jou G." last="Jonasson">Jou G. Jonasson</name><affiliation wicri:level="1"><inist:fA14 i1="19"><s1>Icelandic Cancer Registry, Icelandic Cancer Society</s1><s2>Reykjavik</s2><s3>ISL</s3><sZ>15 aut.</sZ></inist:fA14><country>Islande</country><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="20"><s1>Faculty of Medicine, University of Iceland</s1><s2>Reykjavik</s2><s3>ISL</s3><sZ>15 aut.</sZ></inist:fA14><country>Islande</country><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Martos, Carmen" sort="Martos, Carmen" uniqKey="Martos C" first="Carmen" last="Martos">Carmen Martos</name><affiliation wicri:level="1"><inist:fA14 i1="21"><s1>Cancer Registry of Zaragoza, Health Department of Aragon Government</s1><s2>Zaragoza</s2><s3>ESP</s3><sZ>16 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Zaragoza</wicri:noRegion></affiliation></author><author><name sortKey="Brennan, Paul" sort="Brennan, Paul" uniqKey="Brennan P" 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sort="Scelo, Ghislaine" uniqKey="Scelo G" first="Ghislaine" last="Scelo">Ghislaine Scelo</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>International Agency for Research on Cancer (IARC)</s1><s2>Lyon</s2><s3>FRA</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>17 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Boffetta, Paolo" sort="Boffetta, Paolo" uniqKey="Boffetta P" first="Paolo" last="Boffetta">Paolo Boffetta</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>International Agency for Research on Cancer (IARC)</s1><s2>Lyon</s2><s3>FRA</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>17 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author><author><name sortKey="Hemminki, Kari" sort="Hemminki, Kari" uniqKey="Hemminki K" first="Kari" last="Hemminki">Kari Hemminki</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ)</s1><s2>Heidelberg</s2><s3>DEU</s3><sZ>4 aut.</sZ></inist:fA14><country>Allemagne</country><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Center for Family Medicine, Karolinska Institute</s1><s2>Huddinge</s2><s3>SWE</s3><sZ>4 aut.</sZ></inist:fA14><country>Suède</country><wicri:noRegion>Huddinge</wicri:noRegion></affiliation></author><author><name sortKey="Pukkala, Eero" sort="Pukkala, Eero" uniqKey="Pukkala E" first="Eero" last="Pukkala">Eero Pukkala</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Finnish Cancer Registry, Institute for Statistical and Epidemiology Cancer Research</s1><s2>Helsinki</s2><s3>FIN</s3><sZ>5 aut.</sZ></inist:fA14><country>Finlande</country><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Olsen, Jorgen H" sort="Olsen, Jorgen H" uniqKey="Olsen J" first="Jorgen H." last="Olsen">Jorgen H. Olsen</name><affiliation wicri:level="3"><inist:fA14 i1="06"><s1>Institute of Cancer Epidemiology, Danish Cancer Society</s1><s2>Copenhagen</s2><s3>DNK</s3><sZ>6 aut.</sZ></inist:fA14><country>Danemark</country><placeName><settlement type="city">Copenhague</settlement><region type="région" nuts="2">Hovedstaden</region></placeName></affiliation></author><author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name><affiliation wicri:level="3"><inist:fA14 i1="07"><s1>The Cancer Registry of Norway</s1><s2>Oslo</s2><s3>NOR</s3><sZ>7 aut.</sZ></inist:fA14><country>Norvège</country><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation><affiliation wicri:level="3"><inist:fA14 i1="08"><s1>Department of Medical Epidemiology and Biostatistics, Karolinska Institute</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>7 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Tracey, Elizabeth" sort="Tracey, Elizabeth" uniqKey="Tracey E" first="Elizabeth" last="Tracey">Elizabeth Tracey</name><affiliation wicri:level="1"><inist:fA14 i1="09"><s1>New South Wales Cancer Registry</s1><s2>Eveleigh, NSW</s2><s3>AUS</s3><sZ>8 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>New South Wales Cancer Registry</wicri:noRegion></affiliation></author><author><name sortKey="Brewster, David H" sort="Brewster, David H" uniqKey="Brewster D" first="David H." last="Brewster">David H. Brewster</name><affiliation wicri:level="1"><inist:fA14 i1="10"><s1>Scottish Cancer Registry, Information Services, NHS National Services Scotland</s1><s2>Edinburgh, Scotland</s2><s3>GBR</s3><sZ>9 aut.</sZ></inist:fA14><country>Royaume-Uni</country><wicri:noRegion>Edinburgh, Scotland</wicri:noRegion></affiliation></author><author><name sortKey="Mcbride, Mary L" sort="Mcbride, Mary L" uniqKey="Mcbride M" first="Mary L." last="Mcbride">Mary L. Mcbride</name><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>British Columbia Cancer Agency</s1><s2>Vancouver, BC</s2><s3>CAN</s3><sZ>10 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>British Columbia Cancer Agency</wicri:noRegion></affiliation></author><author><name sortKey="Kliewer, Erich V" sort="Kliewer, Erich V" uniqKey="Kliewer E" first="Erich V." last="Kliewer">Erich V. Kliewer</name><affiliation wicri:level="1"><inist:fA14 i1="12"><s1>Epidemiology and Cancer Registry, CancerCare Manitoba</s1><s2>Winnipeg, MB</s2><s3>CAN</s3><sZ>11 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Winnipeg, MB</wicri:noRegion></affiliation><affiliation wicri:level="4"><inist:fA14 i1="13"><s1>Community Health Sciences, University of Manitoba</s1><s2>Winnipeg, MB</s2><s3>CAN</s3><sZ>11 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Winnipeg</settlement><region type="state">Manitoba</region></placeName><orgName type="university">Université du Manitoba</orgName></affiliation><affiliation wicri:level="4"><inist:fA14 i1="14"><s1>School of Public Health, University of Sydney</s1><s2>Sydney</s2><s3>AUS</s3><sZ>11 aut.</sZ></inist:fA14><country>Australie</country><placeName><settlement type="city">Sydney</settlement><region type="état">Nouvelle-Galles du Sud</region><settlement type="city">Sydney</settlement></placeName><orgName type="university">Université de Sydney</orgName></affiliation></author><author><name sortKey="Tonita, Jon M" sort="Tonita, Jon M" uniqKey="Tonita J" first="Jon M." last="Tonita">Jon M. Tonita</name><affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Saskatchewan Cancer Agency</s1><s2>Regina, SK</s2><s3>CAN</s3><sZ>12 aut.</sZ></inist:fA14><country>Canada</country><wicri:noRegion>Saskatchewan Cancer Agency</wicri:noRegion></affiliation></author><author><name sortKey="Pompe Kirn, Vera" sort="Pompe Kirn, Vera" uniqKey="Pompe Kirn V" first="Vera" last="Pompe-Kirn">Vera Pompe-Kirn</name><affiliation wicri:level="1"><inist:fA14 i1="16"><s1>Cancer Registry of Slovenia, Institute of Oncology</s1><s2>Ljubljana</s2><s3>SVN</s3><sZ>13 aut.</sZ></inist:fA14><country>Slovénie</country><wicri:noRegion>Ljubljana</wicri:noRegion></affiliation></author><author><name sortKey="Kee Seng, Chia" sort="Kee Seng, Chia" uniqKey="Kee Seng C" first="Chia" last="Kee-Seng">Chia Kee-Seng</name><affiliation wicri:level="1"><inist:fA14 i1="17"><s1>Center for Molecular Epidemiology</s1><s3>SGP</s3><sZ>14 aut.</sZ></inist:fA14><country>Singapour</country><wicri:noRegion>Center for Molecular Epidemiology</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="18"><s1>Singapore Cancer Registry</s1><s3>SGP</s3><sZ>14 aut.</sZ></inist:fA14><country>Singapour</country><wicri:noRegion>Singapore Cancer Registry</wicri:noRegion></affiliation></author><author><name sortKey="Jonasson, Jou G" sort="Jonasson, Jou G" uniqKey="Jonasson J" first="Jou G." last="Jonasson">Jou G. Jonasson</name><affiliation wicri:level="1"><inist:fA14 i1="19"><s1>Icelandic Cancer Registry, Icelandic Cancer Society</s1><s2>Reykjavik</s2><s3>ISL</s3><sZ>15 aut.</sZ></inist:fA14><country>Islande</country><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation><affiliation wicri:level="1"><inist:fA14 i1="20"><s1>Faculty of Medicine, University of Iceland</s1><s2>Reykjavik</s2><s3>ISL</s3><sZ>15 aut.</sZ></inist:fA14><country>Islande</country><wicri:noRegion>Reykjavik</wicri:noRegion></affiliation></author><author><name sortKey="Martos, Carmen" sort="Martos, Carmen" uniqKey="Martos C" first="Carmen" last="Martos">Carmen Martos</name><affiliation wicri:level="1"><inist:fA14 i1="21"><s1>Cancer Registry of Zaragoza, Health Department of Aragon Government</s1><s2>Zaragoza</s2><s3>ESP</s3><sZ>16 aut.</sZ></inist:fA14><country>Espagne</country><wicri:noRegion>Zaragoza</wicri:noRegion></affiliation></author><author><name sortKey="Brennan, Paul" sort="Brennan, Paul" uniqKey="Brennan P" first="Paul" last="Brennan">Paul Brennan</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>International Agency for Research on Cancer (IARC)</s1><s2>Lyon</s2><s3>FRA</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>17 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Lyon</settlement></placeName></affiliation></author></analytic><series><title level="j" type="main">International journal of cancer</title><title level="j" type="abbreviated">Int. j. cancer</title><idno type="ISSN">0020-7136</idno><imprint><date when="2007">2007</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">International journal of cancer</title><title level="j" type="abbreviated">Int. j. cancer</title><idno type="ISSN">0020-7136</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antineoplastic agent</term><term>Cancerology</term><term>Chemotherapy</term><term>Epidemiology</term><term>Human</term><term>International</term><term>Leukemia</term><term>Radiotherapy</term><term>Register</term><term>Risk factor</term><term>Second cancer</term><term>Survivor</term><term>Testicle cancer</term><term>Testicular germ cell tumor</term><term>Treatment</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Second cancer</term><term>Survivant</term><term>Registre</term><term>Traitement</term><term>Anticancéreux</term><term>Cancer testicule</term><term>Radiothérapie</term><term>Leucémie</term><term>Facteur risque</term><term>Cancérologie</term><term>Chimiothérapie</term><term>International</term><term>Epidémiologie</term><term>Homme</term><term>Tumeur germinale du testicule</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We investigated the risk of second malignancies among 29,511 survivors of germ-cell testicular cancer recorded in 13 cancer registries. Standardized incidence ratios (SIRs) were estimated comparing the observed numbers of second malignancies with the expected numbers obtained from sex-, age-, period- and population-specific incidence rates. Seminomas and nonseminomas, the 2 main histological groups of testicular cancer, were analyzed separately. During a median follow-up period of 8.3 years (0-35 years), we observed 1,811 second tumors, with a corresponding SIR of 1.65 (95% confidence interval (CI): 1.57-1.73). Statistically significant increased risks were found for fifteen cancer types, including SIRs of 2.0 or higher for cancers of the stomach, gallbladder and bile ducts, pancreas, bladder, kidney, thyroid, and for soft-tissue sarcoma, nonmelanoma skin cancer and myeloid leukemia. The SIR for myeloid leukemia was 2.39 (95% CI: 1.41-3.77) after seminomas, and 6.77 (95% CI: 4.14-10.5) after nonseminomas. It increased to 37.9 (95% CI: 18.9-67.8; based on 11 observed cases of leukemia) among nonseminoma patients diagnosed since 1990. SIRs for most solid cancers increased with follow-up duration, whereas they did not change with year of testicular cancer diagnosis. Among subjects diagnosed before 1980, 20 year survivors of seminoma had a cumulative risk of solid cancer of 9.6% (95% CI: 8.7-10.5%) vs. 6.5% expected, whereas 20 years survivors of nonseminoma had a risk of 5.0% (95% CI: 4.2-6.0%) vs. 3.1% expected. In conclusion, survivors of testicular cancers have an increased risk of several second primaries, where the effect of the treatment seems to play a major role.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Canada</li><li>Danemark</li><li>Espagne</li><li>Finlande</li><li>France</li><li>Islande</li><li>Italie</li><li>Norvège</li><li>Royaume-Uni</li><li>Singapour</li><li>Slovénie</li><li>Suède</li></country><region><li>Auvergne-Rhône-Alpes</li><li>Bade-Wurtemberg</li><li>District de Karlsruhe</li><li>Hovedstaden</li><li>Manitoba</li><li>Nouvelle-Galles du Sud</li><li>Rhône-Alpes</li><li>Svealand</li><li>Østlandet</li></region><settlement><li>Copenhague</li><li>Heidelberg</li><li>Lyon</li><li>Oslo</li><li>Stockholm</li><li>Sydney</li><li>Winnipeg</li></settlement><orgName><li>Université de Sydney</li><li>Université du Manitoba</li></orgName></list><tree><country name="Italie"><noRegion><name sortKey="Richiardi, Lorenzo" sort="Richiardi, Lorenzo" uniqKey="Richiardi L" first="Lorenzo" last="Richiardi">Lorenzo Richiardi</name></noRegion></country><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Scelo, Ghislaine" sort="Scelo, Ghislaine" uniqKey="Scelo G" first="Ghislaine" last="Scelo">Ghislaine Scelo</name></region><name sortKey="Boffetta, Paolo" sort="Boffetta, Paolo" uniqKey="Boffetta P" first="Paolo" last="Boffetta">Paolo Boffetta</name><name sortKey="Brennan, Paul" sort="Brennan, Paul" uniqKey="Brennan P" first="Paul" last="Brennan">Paul Brennan</name></country><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Hemminki, Kari" sort="Hemminki, Kari" uniqKey="Hemminki K" first="Kari" last="Hemminki">Kari Hemminki</name></region></country><country name="Suède"><noRegion><name sortKey="Hemminki, Kari" sort="Hemminki, Kari" uniqKey="Hemminki K" first="Kari" last="Hemminki">Kari Hemminki</name></noRegion><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name></country><country name="Finlande"><noRegion><name sortKey="Pukkala, Eero" sort="Pukkala, Eero" uniqKey="Pukkala E" first="Eero" last="Pukkala">Eero Pukkala</name></noRegion></country><country name="Danemark"><region name="Hovedstaden"><name sortKey="Olsen, Jorgen H" sort="Olsen, Jorgen H" uniqKey="Olsen J" first="Jorgen H." last="Olsen">Jorgen H. Olsen</name></region></country><country name="Norvège"><region name="Østlandet"><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name></region></country><country name="Australie"><noRegion><name sortKey="Tracey, Elizabeth" sort="Tracey, Elizabeth" uniqKey="Tracey E" first="Elizabeth" last="Tracey">Elizabeth Tracey</name></noRegion><name sortKey="Kliewer, Erich V" sort="Kliewer, Erich V" uniqKey="Kliewer E" first="Erich V." last="Kliewer">Erich V. Kliewer</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Brewster, David H" sort="Brewster, David H" uniqKey="Brewster D" first="David H." last="Brewster">David H. Brewster</name></noRegion></country><country name="Canada"><noRegion><name sortKey="Mcbride, Mary L" sort="Mcbride, Mary L" uniqKey="Mcbride M" first="Mary L." last="Mcbride">Mary L. Mcbride</name></noRegion><name sortKey="Kliewer, Erich V" sort="Kliewer, Erich V" uniqKey="Kliewer E" first="Erich V." last="Kliewer">Erich V. Kliewer</name><name sortKey="Kliewer, Erich V" sort="Kliewer, Erich V" uniqKey="Kliewer E" first="Erich V." last="Kliewer">Erich V. Kliewer</name><name sortKey="Tonita, Jon M" sort="Tonita, Jon M" uniqKey="Tonita J" first="Jon M." last="Tonita">Jon M. Tonita</name></country><country name="Slovénie"><noRegion><name sortKey="Pompe Kirn, Vera" sort="Pompe Kirn, Vera" uniqKey="Pompe Kirn V" first="Vera" last="Pompe-Kirn">Vera Pompe-Kirn</name></noRegion></country><country name="Singapour"><noRegion><name sortKey="Kee Seng, Chia" sort="Kee Seng, Chia" uniqKey="Kee Seng C" first="Chia" last="Kee-Seng">Chia Kee-Seng</name></noRegion><name sortKey="Kee Seng, Chia" sort="Kee Seng, Chia" uniqKey="Kee Seng C" first="Chia" last="Kee-Seng">Chia Kee-Seng</name></country><country name="Islande"><noRegion><name sortKey="Jonasson, Jou G" sort="Jonasson, Jou G" uniqKey="Jonasson J" first="Jou G." last="Jonasson">Jou G. Jonasson</name></noRegion><name sortKey="Jonasson, Jou G" sort="Jonasson, Jou G" uniqKey="Jonasson J" first="Jou G." last="Jonasson">Jou G. Jonasson</name></country><country name="Espagne"><noRegion><name sortKey="Martos, Carmen" sort="Martos, Carmen" uniqKey="Martos C" first="Carmen" last="Martos">Carmen Martos</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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